问让 Nginx 重新加载配置时报错怎么办？

[root@VM_0_16_centos ~]# nginx -s reload

nginx: [emerg] BIO_new_file("/etc/nginx/1_www.example.com_bundle.crt") failed (SSL: error:02001002:system library:fopen:No such file or directory:fopen('/etc/nginx/1_www.example.com_bundle.crt','r') error:2006D080:BIO routines:BIO_new_file:no such file)