在生命科学研究中,细胞核的可视化与定位是细胞生物学、分子生物学等领域的基础实验需求,广泛应用于细胞凋亡检测、细胞周期分析、荧光共定位等研究方向。传统核染色试剂存在荧光强度低、特异性差、与其他荧光基团兼容性不足等问题,限制了多色荧光实验的开展。DAPI 作为一种经典的 DNA 特异性染料,凭借其独特的光谱特性和高亲和力,成为解决上述问题的理想选择,已逐渐发展为科研领域常用的核复染工具。
Circular RNA ACVR2A promotes the progression of hepatocellular carcinoma through mir-511-5p targeting PI3K-Akt signaling pathway
期刊:Molecular Cancer(2024)
IF:27.7
DOI:10.1186/s12943-024-02074-z
A multifunctional nanoplatform with dual-targeted antibacterial and cascaded immunomodulatory strategy for the treatment of bacterial keratitis
期刊:CHEMICAL ENGINEERING JOURNAL(2024)
IF:13.3
DOI:10.1016/j.cej.2024.155323
The Six-Transmembrane Epithelial Antigen of the Prostate (STEAP) 3 Regulates the Myogenic Differentiation of Yunan Black Pig Muscle Satellite Cells (MuSCs) In Vitro via Iron Homeostasis and the PI3K/AKT Pathway
期刊:Cells(2025)
IF:5.1
DOI:10.3390/cells14090656
Reversing Microglial Polarisation by High Intensity Interval Training: A Novel Approach to Mitigate Inflammatory Responses in Osteoarthritis via Jak2/Stat3 Pathway
期刊:IMMUNOLOGY(2025)
IF:4.9
DOI:10.1111/imm.13921
Ursolic acid improves necroptosis via STAT3 signaling in intestinal ischemia/reperfusion injury
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY(2024)
IF:4.8
DOI:10.1016/j.intimp.2024.112463